PA551136

IGF2BP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551136-Each-of-1 In Stock ₹ 48,104.50

PA551136 - Each of 1

₹ 48,104.50

In Stock

Quantity

1

Base Price: ₹ 48,104.50

GST (18%): ₹ 8,658.81

Total Price: ₹ 56,763.31

Antigen

IGF2BP3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IGF2BP3

Gene Alias

2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; cancer/testis antigen 98; CT98; hKOC; IGF2 mRNA-binding protein 3; IGF2BP3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; Koc13; mimp3; mIMP-3; Neilsen; RGD1306512; VICKZ family member 3; Vickz3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10643

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.9 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O00425

Gene Symbols

IGF2BP3

Immunogen

Fusion protein of human IGF2BP3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total IGF2BP3 protein
  • Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies
  • IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas
  • IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.