PI700360

MDA5 Recombinant Rabbit Monoclonal Antibody (33H12L34), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI700360-Each-of-1 In Stock ₹ 53,489.00

PI700360 - Each of 1

₹ 53,489.00

In Stock

Quantity

1

Base Price: ₹ 53,489.00

GST (18%): ₹ 9,628.02

Total Price: ₹ 63,117.02

Antigen

MDA5

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8R5F7, Q9BYX4

Gene Symbols

IFIH1

Immunogen

A recombinant protein corresponding to amino acids 883-1025 of Q9BYX4.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunoprecipitation, Western Blot

Clone

33H12L34

Conjugate

Unconjugated

Gene

IFIH1

Gene Alias

9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

64135, 71586

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Rhesus monkey, mouse, rat, porcine and bovine based on sequence homology
  • Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein
  • Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.