CD53 Monoclonal Antibody (MEM-53), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA110247-Each-of-1 | In Stock | ₹ 38,448.00 |
PIMA110247 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,448.00
GST (18%): ₹ 6,920.64
Total Price: ₹ 45,368.64
Antigen
CD53
Classification
Monoclonal
Conjugate
FITC
Gene
Cd53
Gene Alias
AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
963
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MEM-53
Formulation
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P19397
Gene Symbols
Cd53
Immunogen
Leukocytes of pacient suffering from a LGL-type leukemia.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- This antibody reacts with CD53, a 32-40 kDa glycoprotein, and also This antibody reacts with the deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F)
- CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage
- This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes
- CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect
- In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.