PIMA126438

Phosphatidylinositol 4,5-biphosphate Monoclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA126438-Each-of-1 In Stock ₹ 50,062.50

PIMA126438 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

Phosphatidylinositol 4,5-biphosphate

Classification

Monoclonal

Conjugate

Unconjugated

Gene Alias

C45H85O19P3; PIP2

Immunogen

Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord.

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Target Molecule

Chemical

Applications

ELISA, Radioimmune Assays (RIA)

Concentration

1 mg/mL

Formulation

PBS with 10% BSA and 0.05% sodium azide

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG2b

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Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Phosphatidylinositol 4,5-bisphosphate or PIP2 is an important second messenger for a number of signaling processes
  • When certain extracellular signals are received, Phosphilipase C cleaves phosphatidylinositol into DAG and PIP2
  • PIP2 has been shown to interact with actin structural proteins including profiling, gelsolin, and cofilin, and demonstrates regulatory function of actin polymerization
  • It has also been shown to regulate vesicular transport by interacting with proteins like ADP-ribosylation factor and phospholipase D
  • PIP2 has also been shown to significantly affect intracellular calcium concentrations, which also regulate a variety of activities.