PIMA183519
Cholera Toxin beta Monoclonal Antibody (2/63), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA183519-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA183519 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
Cholera Toxin beta
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Bacteria
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunohistochemistry (Frozen)
Clone
2/63
Conjugate
Unconjugated
Gene Alias
CTB; CTX; VC1456
Immunogen
Vibrio cholerae.
Quantity
200 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse anti Cholera Toxin beta antibody, clone 2/63 detects the labile enterotoxin normally associated with V
- cholera and reacts with an epitope on the B chain.No reactivity was observed with other species tested including various E
- coli serotypes
- Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae
- CTX is the causative agent of cholera infection
- The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge
- The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP
- The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells
- The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.