PIMA181921
Epstein Barr Virus LMP2A Monoclonal Antibody (15F9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA181921-Each-of-1 | In Stock | ₹ 50,774.50 |
PIMA181921 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,774.50
GST (18%): ₹ 9,139.41
Total Price: ₹ 59,913.91
Antigen
Epstein Barr Virus LMP2A
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
15F9
Conjugate
Unconjugated
Gene Alias
EBV
Immunogen
Bacterial TrpE-LMP2A fusion protein.
Quantity
250 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections
- Rat anti Epstein-Barr Virus LMP2A antibody, clone 15F9 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV)
- Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents
- EBV latently infects B lymphocytes
- Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B
- LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases
- Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.