PIMA181963
TLR7 Monoclonal Antibody (4F4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA181963-Each-of-1 | In Stock | ₹ 55,714.00 |
PIMA181963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,714.00
GST (18%): ₹ 10,028.52
Total Price: ₹ 65,742.52
Antigen
TLR7
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 10% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9NYK1
Gene Symbols
TLR7
Immunogen
Recombinant human TLR7 (aa451-500) purified from E. coli
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Western Blot
Clone
4F4
Conjugate
Unconjugated
Gene
TLR7
Gene Alias
RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
51284
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- In Western blot, this antibody detects a band at ∽121 kDa in Ramos cell lysate
- Mouse anti Human TLR7 antibody, clone 4F4 recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein belonging to the toll-like receptor (TLR) family
- TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain
- TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity
- TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV)
- TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8
- TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response
- TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.