TLR7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA128109-Each-of-1 | In Stock | ₹ 49,528.50 |
PIPA128109 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,528.50
GST (18%): ₹ 8,915.13
Total Price: ₹ 58,443.63
Antigen
TLR7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLR7
Gene Alias
RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
170743, 317468, 51284
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P58681, Q9NYK1
Gene Symbols
TLR7
Immunogen
This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 706-749 of human TLR7.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- This antibody will cross-react with mouse TLR7
- In human Ramos cells, additional bands are seen
- TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain
- TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity
- TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV)
- TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8
- TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response
- TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.