TEM7 Monoclonal Antibody (197C193), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA191725-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA191725 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
TEM7
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.
Q8IUK5, Q91ZV7
Gene Symbols
PLXDC1
Immunogen
Amino acids 409-425 (LQNNLSPKTKGTPVHLG) of human TEM7 were used to develop this monoclonal antibody.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
197C193
Conjugate
Unconjugated
Gene
PLXDC1
Gene Alias
2410003I07Rik; ADP-ribosylation factor-like 12; AI848450; Arl12; DKFZp686F0937; FLJ36270; FLJ45632; plexin domain containing 1; plexin domain-containing protein 1; PLXDC1; TEM3; TEM7; TEM7 related; tumor endothelial marker 3; Tumor endothelial marker 7; tumor endothelial marker7
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
303505, 57125, 72324
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-91725 detects TEM7 from human samples
- Recently, using SAGE (Serial Analysis of Gene Expression) technology, St
- Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium
- Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9)
- TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain
- TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis
- The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis
- Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.