PIMA191751

ACVR2A Monoclonal Antibody (149/1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA191751-Each-of-1 In Stock ₹ 49,884.50

PIMA191751 - Each of 1

₹ 49,884.50

In Stock

Quantity

1

Base Price: ₹ 49,884.50

GST (18%): ₹ 8,979.21

Total Price: ₹ 58,863.71

Antigen

ACVR2A

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P27037, P38444

Gene Symbols

ACVR2A

Immunogen

Recombinant intracellular kinase domain of the human type 2 activin receptor

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

149/1

Conjugate

Unconjugated

Gene

ACVR2A

Gene Alias

activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

29263, 92

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-91751 detects Activin receptor type II from human samples
  • Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases
  • ACVR2A is involved in the activin and myostatin signaling pathway
  • (ACVR2A Aliases: ACVR2, ACTRII)
  • These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
  • Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors
  • Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
  • Type II receptors are considered to be constitutively active kinases.