PIPA514921

ACVRL1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA514921-Each-of-1 In Stock ₹ 48,816.50

PIPA514921 - Each of 1

₹ 48,816.50

In Stock

Quantity

1

Base Price: ₹ 48,816.50

GST (18%): ₹ 8,786.97

Total Price: ₹ 57,603.47

Antigen

ACVRL1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ACVRL1

Gene Alias

activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

11482, 94

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.0 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P37023, Q61288

Gene Symbols

ACVRL1

Immunogen

KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human ACVRL1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands
  • ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail
  • Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2
  • Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.