PIMA541541

ACVR2A Monoclonal Antibody (C11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541541-Each-of-1 In Stock ₹ 45,790.50

PIMA541541 - Each of 1

₹ 45,790.50

In Stock

Quantity

1

Base Price: ₹ 45,790.50

GST (18%): ₹ 8,242.29

Total Price: ₹ 54,032.79

Antigen

ACVR2A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P27037

Gene Symbols

ACVR2A

Immunogen

Recombinant protein Activin A Receptor Type II A. The antigen corresponds to amino acid range 20-135 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

C11

Conjugate

Unconjugated

Gene

ACVR2A

Gene Alias

activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

92

Content And Storage

-20°C

Form

Liquid

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Description

  • Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases
  • ACVR2A is involved in the activin and myostatin signaling pathway
  • (ACVR2A Aliases: ACVR2, ACTRII)
  • These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
  • Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors
  • Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
  • Type II receptors are considered to be constitutively active kinases.