Vimentin Monoclonal Antibody (V9), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511880-Each-of-1 | In Stock | ₹ 48,460.50 |
PIMA511880 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,460.50
GST (18%): ₹ 8,722.89
Total Price: ₹ 57,183.39
Antigen
Vimentin
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P02543, P08670, P09654, P20152, P31000, P48616, P48670
Gene Symbols
Vim
Immunogen
Purified vimentin from pig eye lens
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Chicken, Equine, Feline, Gerbil, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin)
Clone
V9
Conjugate
Biotin
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100008924, 100056088, 100522394, 100689099, 101091951, 22352, 280955, 420519, 477991, 7431, 81818
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-11880 targets Vimentin in immunohistochemistry (paraffin) applications and shows reactivity with Bovine, Canine, Chicken, Equine, Feline, Gerbil, Hamster, Human, mouse, Non-human primate, Porcine, Rabbit, and Rat samples
- The MA5-11880 immunogen is purified vimentin from pig eye lens
- Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH6.0, for 10-20 minutes followed by cooling at RT for 20 min
- Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.