PIMA511803
Involucrin Monoclonal Antibody (SY5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511803-Each-of-1 | In Stock | ₹ 52,421.00 |
PIMA511803 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,421.00
GST (18%): ₹ 9,435.78
Total Price: ₹ 61,856.78
Antigen
Involucrin
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.
P07476, P18174, P18175, P48998
Gene Symbols
IVL
Immunogen
Human keratinocytes' involucrin
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Non-human Primate, Porcine, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
SY5
Conjugate
Unconjugated
Gene
IVL
Gene Alias
1110019C06Rik; involucrin; IVL
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
101125010, 102152041, 3713, 407242, 60583
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-11803 targets Involucrin in ELISA, IF, IHC (P), IP, and WB applications and shows reactivity with Canine, Human, Non-human primate, Porcine, and Rat samples
- The MA5-11803 immunogen is human keratinocytes' involucrin
- Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase
- Involucrin is expressed in a range of stratified squamous epithelia, including the cornea
- In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer
- Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions and is reduced in severe dysplasias of the larynx and cervix
- Its gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.