SAPK4 Monoclonal Antibody (R.618.4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514994-Each-of-1 | In Stock | ₹ 41,385.00 |
PIMA514994 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
SAPK4
Classification
Monoclonal
Conjugate
Unconjugated
Gene
MAPK13
Gene Alias
im:7136778; MAP kinase 13; MAP kinase p38 delta; MAPK 13; Mapk13; MAPK-13; mitogen activated protein kinase 13; mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta MAP kinase; p38delta; PRKM13; SAPK/Erk/kinase 4; SAPK4; Serk4; Stress-activated protein kinase 4
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29513, 5603
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Clone
R.618.4
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
O15264, Q9WTY9
Gene Symbols
MAPK13
Immunogen
Synthetic peptide corresponding to residues around the carboxy terminus of p38d MAPK
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other isoforms of p38 MAPK
- MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses
- MAPK13 also regulates the differentiation of keratinocytes
- This kinase is activated by various environmental stresses and proinflammatory cytokines
- The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase
- The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response
- Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.