ELK1 Monoclonal Antibody (3H6D12, 4H9C8, 4H9F1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515310-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515310 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
ELK1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P19419
Gene Symbols
ELK1
Immunogen
Purified recombinant fragment of ELK1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
2002
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
3H6D12, 4H9C8, 4H9F1, 4H9C8, 4H9F1
Conjugate
Unconjugated
Gene
ELK1
Gene Alias
ELK 1; ELK1; Elk-1; ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS transcription factor ELK1; ETS-like gene 1; Oncogene Elk1; tyrosine kinase (ELK1) oncogene
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15310 targets ELK1 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15310 immunogen is purified recombinant fragment of ELK1 expressed in E
- Coli
- ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors
- ELK1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus
- Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by ELK1
- ELK1 appears to be a direct target of activated MAP kinase
- Biochemical studies indicate that ELK1 is a good substrate for MAP kinase, the kinetics of ELK1 phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block ELK1 activation in vivo
- ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade
- Alternatively spliced transcript variants encoding the same protein have been found for ELK1.