PIMA515527

PAK2 Monoclonal Antibody (3B5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515527-Each-of-1 In Stock ₹ 50,151.50

PIMA515527 - Each of 1

₹ 50,151.50

In Stock

Quantity

1

Base Price: ₹ 50,151.50

GST (18%): ₹ 9,027.27

Total Price: ₹ 59,178.77

Antigen

PAK2

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q13177

Gene Symbols

Pak2

Immunogen

Purified recombinant fragment of PAK2 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

5062

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3B5

Conjugate

Unconjugated

Gene

Pak2

Gene Alias

5330420P17Rik; A130002K10Rik; AI836325; Alpha-PAK; Beta-PAK; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p27; p34; p58; p65-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; PAKgamma; S6/H4 kinase; serine/threonine-protein kinase PAK 2

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15527 targets PAK2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples
  • The MA5-15527 immunogen is purified recombinant fragment of PAK2 expressed in E
  • Coli
  • MA5-15527 detects PAK2 which has a predicted molecular weight of approximately 61kDa
  • PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, or proliferation
  • It acts as a downstream effector of the small GTPases CDC42 and RAC1
  • Activation by the binding of active CDC42 and RAC1 results in a conformation change and a subsequent autophosphorylation on several serine and/or threonine residues
  • Full-length PAK2 stimulates cell survival and cell growth
  • PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
  • PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.