CDK9 Monoclonal Antibody (1B5A7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515849-Each-of-1 | In Stock | ₹ 55,714.00 |
PIMA515849 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,714.00
GST (18%): ₹ 10,028.52
Total Price: ₹ 65,742.52
Antigen
CDK9
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P50750
Gene Symbols
CDK9
Immunogen
Purified recombinant fragment of human CDK9 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
1025
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
1B5A7
Conjugate
Unconjugated
Gene
CDK9
Gene Alias
C-2k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15849 targets CDK9 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15849 immunogen is purified recombinant fragment of human CDK9 expressed in E
- Coli
- MA5-15849 detects CDK9 which has a predicted molecular weight of approximately 43kDa
- CDK9 is a serine/threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex
- This complex plays a key role in regulating the eukaryotic cell cycle
- CDK9 is coexpressed and copurified with CyclinT1
- CDK9 regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors
- CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis
- The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro
- Chronic activation of CDK9 causes cardiac myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.