PR3 Monoclonal Antibody (3B4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515540-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515540 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
PR3
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 50% glycerol and 0.03% sodium azide
Gene Accession No.
P24158
Gene Symbols
PRTN3
Immunogen
Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Western Blot
Clone
3B4
Conjugate
Unconjugated
Gene
PRTN3
Gene Alias
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5657
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-15540 targets Proteinase 3 in indirect ELISA, WB applications and shows reactivity with Human samples
- The MA5-15540 immunogen is purified recombinant fragment of human Proteinase 3 expressed in E
- Coli
- MA5-15540 detects Proteinase 3 which has a predicted molecular weight of approximately 28kDa
- Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246)
- By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369)
- May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279)
- [UniProt]