VEGF Receptor 1 Monoclonal Antibody (3D10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515550-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515550 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
VEGF Receptor 1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P17948
Gene Symbols
FLT1
Immunogen
Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
Regulatory Status
RUO
Gene ID (Entrez)
2321
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Clone
3D10
Conjugate
Unconjugated
Gene
FLT1
Gene Alias
AI323757; embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15550 targets FLT1 in indirect ELISA, WB applications and shows reactivity with Human samples
- The MA5-15550 immunogen is purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells
- MA5-15550 detects FLT1 which has a predicted molecular weight of approximately 100kDa
- FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis
- Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing
- May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells
- Can promote endothelial cell proliferation, survival and angiogenesis in adulthood
- Its function in promoting cell proliferation seems to be cell-type specific
- Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro)
- Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.