PIMA515543

TrkC Monoclonal Antibody (7H6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515543-Each-of-1 In Stock ₹ 50,507.50

PIMA515543 - Each of 1

₹ 50,507.50

In Stock

Quantity

1

Base Price: ₹ 50,507.50

GST (18%): ₹ 9,091.35

Total Price: ₹ 59,598.85

Antigen

TrkC

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q16288

Gene Symbols

Ntrk3

Immunogen

Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Regulatory Status

RUO

Gene ID (Entrez)

4916

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

7H6

Conjugate

Unconjugated

Gene

Ntrk3

Gene Alias

AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15543 targets NTRK3 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
  • The MA5-15543 immunogen is purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells
  • MA5-15543 detects NTRK3 which has a predicted molecular weight of approximately 94kDa
  • NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1
  • The different isoforms do not have identical signaling properties
  • The protein is widely expressed, mainly in the nervous tissue
  • The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain
  • TRKC is subject to ligand-mediated auto-phosphorylation
  • The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.