PGA5 Monoclonal Antibody (2C1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515558-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515558 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
PGA5
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P0DJD9
Gene Symbols
Pga5
Immunogen
Purified recombinant fragment of human PGA5 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
5222
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
2C1
Conjugate
Unconjugated
Gene
Pga5
Gene Alias
1110035E17Rik; Pepf; pepsin A; pepsin A-5; Pepsin F; Pepsinogen 5; pepsinogen 5, group I; pepsinogen 5, group I (pepsinogen A); pepsinogen A; pepsinogen A precursor; pepsinogen A5; pepsinogen F; pepsinogen F protein; pepsinogen precursor; pepsinogen-5; Pg5; PGA; PGA3; PGA4; PGA5
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15558 targets PGA5 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15558 immunogen is purified recombinant fragment of human PGA5 expressed in E
- Coli
- MA5-15558 detects PGA5 which has a predicted molecular weight of approximately 42kDa
- PGA5: Pepsinogen 5, group I (pepsinogen A)
- Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach
- Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa
- Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus
- Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function
- Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids
- Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent
- PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates
- PGA5 is inhibited by ovUS-1, a uterine serpin.