GATA3 Monoclonal Antibody (7B5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515641-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515641 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
GATA3
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P23771
Gene Symbols
GATA3
Immunogen
Purified recombinant fragment of human GATA3 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
2625
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
7B5
Conjugate
Unconjugated
Gene
GATA3
Gene Alias
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15641 targets GATA3 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15641 immunogen is purified recombinant fragment of human GATA3 expressed in E
- Coli
- <br>
- MA5-15641 detects GATA3 which has a predicted molecular weight of approximately 48kDa
- The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
- Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
- GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
- GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
- GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
- Labastie et al
- (1994) cloned the human gene and the 5-prime end of the mouse gene
- The human gene comprises 6 exons distributed over 17 kb of DNA
- Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.