PIMA515387

GATA3 Monoclonal Antibody (1A10D1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515387-Each-of-1 In Stock ₹ 50,240.50

PIMA515387 - Each of 1

₹ 50,240.50

In Stock

Quantity

1

Base Price: ₹ 50,240.50

GST (18%): ₹ 9,043.29

Total Price: ₹ 59,283.79

Antigen

GATA3

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P23771

Gene Symbols

GATA3

Immunogen

Purified recombinant fragment of GATA3 (aa175-388) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

2625

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

1A10D1

Conjugate

Unconjugated

Gene

GATA3

Gene Alias

EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15387 targets GATA3 in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15387 immunogen is purified recombinant fragment of GATA3 (aa175-388) expressed in E
  • Coli
  • The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
  • Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
  • GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
  • GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
  • GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
  • Labastie et al
  • (1994) cloned the human gene and the 5-prime end of the mouse gene
  • The human gene comprises 6 exons distributed over 17 kb of DNA
  • Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.