SIRT1 Monoclonal Antibody (1F3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515677-Each-of-1 | In Stock | ₹ 55,447.00 |
PIMA515677 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,447.00
GST (18%): ₹ 9,980.46
Total Price: ₹ 65,427.46
Antigen
SIRT1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q96EB6
Gene Symbols
SIRT1
Immunogen
Purified recombinant fragment of human SIRT1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
23411
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
1F3
Conjugate
Unconjugated
Gene
SIRT1
Gene Alias
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; SIR2; Sir2a; SIR2alpha; SIR2L1; sir2-like 1; SIR2-like protein 1; SIRT 1; SIRT1; SIRT-1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15677 targets SIRT1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples
- The MA5-15677 immunogen is purified recombinant fragment of human SIRT1 expressed in E
- Coli
- MA5-15677 detects SIRT1 which has a predicted molecular weight of approximately 120kDa
- NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy
- SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression
- It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).