SMN1 Monoclonal Antibody (5H1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515858-Each-of-1 | In Stock | ₹ 56,159.00 |
PIMA515858 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,159.00
GST (18%): ₹ 10,108.62
Total Price: ₹ 66,267.62
Antigen
SMN1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q16637
Gene Symbols
SMN1
Immunogen
Purified recombinant fragment of human SMN1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
6606
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
5H1
Conjugate
Unconjugated
Gene
SMN1
Gene Alias
AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15858 targets SMN1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples
- The MA5-15858 immunogen is purified recombinant fragment of human SMN1 expressed in E
- Coli
- MA5-15858 detects SMN1 which has a predicted molecular weight of approximately 39kDa
- The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13
- This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions
- The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region
- The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein
- The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome
- Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.