GFI1 Monoclonal Antibody (5D7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515688-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515688 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
GFI1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q99684
Gene Symbols
GFI1
Immunogen
Purified recombinant fragment of human GFI1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
2672
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Clone
5D7
Conjugate
Unconjugated
Gene
GFI1
Gene Alias
AW495828; FLJ94509; Gfi1; GFI-1; GFI1A; growth factor independence-1; growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent 1 transcriptional repressor; growth factor independent protein 1; Growth factor independent-1; Pal1; Pal-1; SCN2; Zinc finger protein 163; zinc finger protein Gfi-1; ZNF163
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15688 targets GFI1 in indirect ELISA, WB applications and shows reactivity with Human samples
- The MA5-15688 immunogen is purified recombinant fragment of human GFI1 expressed in E
- Coli
- MA5-15688 detects GFI1 which has a predicted molecular weight of approximately 45kDa
- GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis
- The Gfi1 protein expression is regulated by the ubiquitin-proteasome system
- It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1
- Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes
- Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.