B7-H3 Monoclonal Antibody (6A1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515693-Each-of-1 | In Stock | ₹ 54,913.00 |
PIMA515693 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,913.00
GST (18%): ₹ 9,884.34
Total Price: ₹ 64,797.34
Antigen
B7-H3
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q5ZPR3
Gene Symbols
CD276
Immunogen
Purified recombinant fragment of human CD276 (A.A. 30-130) expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
80381
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
6A1
Conjugate
Unconjugated
Gene
CD276
Gene Alias
4Ig-B7-H3; 6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP-2; CD276; CD276 antigen; CD276 molecule; CD276 molecule tv1; costimulatory molecule; PSEC0249; sB7 H3; sB7H3; sCD276; soluble B7 H3; soluble B7H3; soluble CD276; UNQ309/PRO352
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15693 targets CD276 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples
- The MA5-15693 immunogen is purified recombinant fragment of human CD276 expressed in E
- Coli
- MA5-15693 detects CD276 which has a predicted molecular weight of approximately 57kDa
- CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3
- CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma
- Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon
- In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing
- CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.