Bim Monoclonal Antibody (1C2C8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515763-Each-of-1 | In Stock | ₹ 50,774.50 |
PIMA515763 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,774.50
GST (18%): ₹ 9,139.41
Total Price: ₹ 59,913.91
Antigen
Bim
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O43521, O54918
Gene Symbols
BCL2L11
Immunogen
Recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
1C2C8
Conjugate
Unconjugated
Gene
BCL2L11
Gene Alias
1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)
Host Species
Mouse
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10018, 12125
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- A suggested positive control is Bim recombinant protein
- BIM belongs to the BCL-2 protein family
- BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities
- The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3)
- It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator
- The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis
- Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection
- Several alternatively spliced transcript variants of this gene have been identified.