PIMA515919

BMI-1 Monoclonal Antibody (3E3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515919-Each-of-1 In Stock ₹ 50,062.50

PIMA515919 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

BMI-1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P25916, P35226

Gene Symbols

BMI1

Immunogen

Purified recombinant fragment of human BMI1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

12151, 648

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3E3

Conjugate

Unconjugated

Gene

BMI1

Gene Alias

AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15919 targets BMI1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples
  • The MA5-15919 immunogen is purified recombinant fragment of human BMI1 expressed in E
  • Coli
  • MA5-15919 detects BMI1 which has a predicted molecular weight of approximately 37kDa
  • Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development
  • PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility
  • In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.