PIMA517186

LAP (Latency Associated Peptide) Monoclonal Antibody (7F6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517186-Each-of-1 In Stock ₹ 49,884.50

PIMA517186 - Each of 1

₹ 49,884.50

In Stock

Quantity

1

Base Price: ₹ 49,884.50

GST (18%): ₹ 8,979.21

Total Price: ₹ 58,863.71

Antigen

LAP (Latency Associated Peptide)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P01137

Gene Symbols

TGFB1

Immunogen

Purified recombinant fragment of human TGFb1 (amino acids: 62-195) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

7F6

Conjugate

Unconjugated

Gene

TGFB1

Gene Alias

CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

7040

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17186 targets TGFb1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples
  • The MA5-17186 immunogen is purified recombinant fragment of human TGFb1 (amino acids: 62-195) expressed in E
  • Coli
  • MA5-17186 detects TGFb1 which has a predicted molecular weight of approximately 44.3kDa
  • TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues
  • Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain
  • Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins
  • Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.