TCF2 Monoclonal Antibody (CL0374), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524605-Each-of-1 | In Stock | ₹ 53,400.00 |
PIMA524605 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,400.00
GST (18%): ₹ 9,612.00
Total Price: ₹ 63,012.00
Antigen
TCF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P35680
Gene Symbols
HNF1B
Immunogen
Recombinant protein corresponding to Human TCF2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
CL0374
Conjugate
Unconjugated
Gene
HNF1B
Gene Alias
FJHN; Hepatocyte nuclear factor 1-beta; hepatocyte nuclear factor-1 beta; HNF1 beta A; HNF1 homeobox B; HNF1B; Hnf-1b; Hnf1beta; HNF-1Beta; HNF-1-beta; HNF2; homeoprotein LFB3; HPC11; LFB3; LF-B3; MODY5; Tcf2; Tcf-2; Transcription factor 2; Transcription factor 2 hepatic; Transcription factor 2 hepatic; LF-B3; variant hepatic nuclear factor; transcription factor 2, hepatic; Transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor; variant hepatic nuclear factor 1; vHNF1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6928
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: KEVLVQALEE LLPSPNFGVK LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL KELQALNTEE AAEQRAEVDR MLSEDPWRAA KMIKGYMQQH Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%
- Binds to an epitope located within the peptide sequence TPPILKELQA as determined by overlapping synthetic peptides
- Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors
- It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family
- The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha
- HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas
- Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer
- Multiple transcript variants encoding different isoforms have been found for this gene.