PIMA524611
SLC22A2 Monoclonal Antibody (CL0628), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524611-Each-of-1 | In Stock | ₹ 53,667.00 |
PIMA524611 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,667.00
GST (18%): ₹ 9,660.06
Total Price: ₹ 63,327.06
Antigen
SLC22A2
Classification
Monoclonal
Concentration
1.00 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O15244
Gene Symbols
Slc22a2
Immunogen
Recombinant protein corresponding to Human SLC22A2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry
Clone
CL0628
Conjugate
Unconjugated
Gene
Slc22a2
Gene Alias
2-Oct; hOCT2; OCT2; OCT2r; Orct2; Organic cation transporter 2; rOCT2; Slc22a2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2; solute carrier family 22, member 2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6582
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: ESPRWLISQN KNAEAMRIIK HIAKKNGKSL PASLQRLRLE EETGKKLNPS FLDLVRTPQI R Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 77%
- Binds to an epitope located within the peptide sequence KNAEAMRIIKHIAKK as determined by overlapping synthetic peptides
- Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics
- The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop
- In humans, OCT1 is primarily expressed in the liver, while OCT2 is expressed in the kidney
- OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver
- OCT2, also known as SLC22A2, is a multi-specific transporter protein localizing to the basolateral and luminal membranes of the kidney distal tubule and proximal tubules
- OCT2 is responsible for mediating the pH-sensitive tubular uptake of organic compounds from circulation
- An additional splice variant exists for OCT2, namely OCT2-A.