KDM5B Monoclonal Antibody (CL1147), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524627-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA524627 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
KDM5B
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9UGL1
Gene Symbols
KDM5B
Immunogen
Recombinant protein corresponding to Human KDM5B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
CL1147
Conjugate
Unconjugated
Gene
KDM5B
Gene Alias
2010009J12Rik; 2210016I17Rik; AW556288; cancer/testis antigen 31; CT31; D1Ertd202e; Histone demethylase JARID1B; Jarid1b; jumonji, AT rich interactive domain 1B; jumonji, AT rich interactive domain 1B (Rbp2 like); Jumonji, AT rich interactive domain 1B (RBP2-like); jumonji/ARID domain-containing protein 1B; KDM5B; Kiaa4034; lysine (K)-specific demethylase 5B; lysine demethylase 5B; lysine-specific demethylase 5B; mKIAA4034; PLU1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; putative DNA/chromatin binding motif 1; Rb-Bp2; RBBP2H1; RBBP2H1A; RBP2-H1; Retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A; RGD1565602
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10765
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: DGINSLERKL KRRLEREGLS SERWERVKKM RTPKKKKIKL SHPKDMNNFK LERERSYELV RSAETHSLPS DTSYSEQEDS E Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 91%
- Binds to an epitope located within the peptide sequence SERWERVKKMRTPKK as determined by overlapping synthetic peptides
- KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code
- It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'
- KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'
- It acts as a transcriptional corepressor for FOXG1B and PAX9
- It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5
- In contrast, KDM5B may act as a tumor suppressor for melanoma.