Livin Monoclonal Antibody (OTI1D12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525012-Each-of-1 | In Stock | ₹ 52,643.50 |
PIMA525012 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,643.50
GST (18%): ₹ 9,475.83
Total Price: ₹ 62,119.33
Antigen
Livin
Classification
Monoclonal
Concentration
0.36 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q96CA5
Gene Symbols
BIRC7
Immunogen
Full length human recombinant protein of BIRC7 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI1D12
Conjugate
Unconjugated
Gene
BIRC7
Gene Alias
baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing 7; baculoviral IAP repeat-containing 7 (livin); baculoviral IAP repeat-containing protein 7; Baculoviral IAP repeat-containing protein 7 30 kDa subunit; Baculoviral IAP repeat-containing protein 7 30kDa subunit; Birc7; E130019N06; KIAP; Kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RGD1562883; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50; RP11-261N11.7; Truncated livin; UNQ5800/PRO19607/PRO21344
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
79444
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli
- All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity
- Recently, it has been identified that a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain
- Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain
- Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells
- Livin expression is low in adult tissues
- It is relatively expressed at a higher level in developmental tissues and in many cancer cells.