PIMA525033

LOX Monoclonal Antibody (OTI9G6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525033-Each-of-1 In Stock ₹ 52,287.50

PIMA525033 - Each of 1

₹ 52,287.50

In Stock

Quantity

1

Base Price: ₹ 52,287.50

GST (18%): ₹ 9,411.75

Total Price: ₹ 61,699.25

Antigen

LOX

Classification

Monoclonal

Concentration

1.00 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P28300

Gene Symbols

LOX

Immunogen

Human recombinant protein fragment corresponding to amino acids 22-168 of LOX produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI9G6

Conjugate

Unconjugated

Gene

LOX

Gene Alias

AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4015

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes
  • It plays a vital role in the formation and repair of the extra cellular matrix
  • As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence
  • The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells
  • Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.