PIMA525075

RIC8A Monoclonal Antibody (OTI3G3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525075-Each-of-1 In Stock ₹ 52,198.50

PIMA525075 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

RIC8A

Classification

Monoclonal

Concentration

0.83 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9NPQ8

Gene Symbols

RIC8A

Immunogen

Full length human recombinant protein of RIC8A produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3G3

Conjugate

Unconjugated

Gene

RIC8A

Gene Alias

AI114950; heterotrimeric G protein guanine nucleotide exchange factor Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; Protein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog; resistance to inhibitors of cholinesterase 8 homolog (C. elegans); resistance to inhibitors of cholinesterase 8 homolog A; resistance to inhibitors of cholinesterase 8A; Ric8; RIC-8; RIC8 guanine nucleotide exchange factor A; RIC8 protein; Ric8a; Ric-8A; synembryn; synembryn-A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

60626

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins
  • Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP
  • Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex
  • Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.