PIMA527874
Emerin Monoclonal Antibody (5A10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527874-Each-of-1 | In Stock | ₹ 44,544.50 |
PIMA527874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,544.50
GST (18%): ₹ 8,018.01
Total Price: ₹ 52,562.51
Antigen
Emerin
Classification
Monoclonal
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P50402
Gene Symbols
Emd
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Emerin (1-48aa MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRL).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
5A10
Conjugate
Unconjugated
Gene
Emd
Gene Alias
AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species
Mouse
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2010
Content And Storage
-20°C
Form
Lyophilized
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
- The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
- Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
- The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
- A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
- A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
- Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.