PIPA579201
Emerin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA579201-Each-of-1 | In Stock | ₹ 43,387.50 |
PIPA579201 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,387.50
GST (18%): ₹ 7,809.75
Total Price: ₹ 51,197.25
Antigen
Emerin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Emd
Gene Alias
AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13726, 2010, 25437
Content And Storage
-20°C
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.
O08579, P50402, Q63190
Gene Symbols
Emd
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Emerin (1-48aa MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRL).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
- The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
- Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
- The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
- A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
- A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
- Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.