PIPA517188

Emerin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517188-Each-of-1 In Stock ₹ 43,476.50

PIPA517188 - Each of 1

₹ 43,476.50

In Stock

Quantity

1

Base Price: ₹ 43,476.50

GST (18%): ₹ 7,825.77

Total Price: ₹ 51,302.27

Antigen

Emerin

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P50402

Gene Symbols

Emd

Immunogen

Synthetic peptide corresponding to residues surrounding Leu12 of human Emerin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

Emd

Gene Alias

AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2010

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
  • The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
  • Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
  • The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
  • A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
  • A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
  • Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.