PIMA529746

ARMET Recombinant Rabbit Monoclonal Antibody (012), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA529746-Each-of-1 In Stock ₹ 41,385.00

PIMA529746 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

ARMET

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q9CXI5

Gene Symbols

MANF

Immunogen

Recombinant Mouse MANF protein (Met1-Leu179)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

ELISA

Clone

012

Conjugate

Unconjugated

Gene

MANF

Gene Alias

3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

74840

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • This antibody has specificity for Mouse MANF
  • The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted
  • Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation
  • The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract
  • The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.