PDPK1 Monoclonal Antibody (3H3D9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531835-Each-of-1 | In Stock | ₹ 49,973.50 |
PIMA531835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,973.50
GST (18%): ₹ 8,995.23
Total Price: ₹ 58,968.73
Antigen
PDPK1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O15530
Gene Symbols
Pdpk1
Immunogen
Purified recombinant fragment of human PDPK1 (AA: 457-556 expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
3H3D9
Conjugate
Unconjugated
Gene
Pdpk1
Gene Alias
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5170
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-31835 has been tested in indirect ELISA
- PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
- PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop
- PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate
- Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis
- Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.