PIMA531995

PI3K p55 gamma Recombinant Rabbit Monoclonal Antibody (SR44-06), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531995-Each-of-1 In Stock ₹ 47,481.50

PIMA531995 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

PI3K p55 gamma

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q63789, Q64143, Q92569

Gene Symbols

Pik3r3

Immunogen

Synthetic peptide within Human PI 3 Kinase p55 gamma aa 429-461.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SR44-06

Conjugate

Unconjugated

Gene

Pik3r3

Gene Alias

AA414954, p55, p55-GAMMA, p55pik, phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55), phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase p55 subunit, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma), phosphoinositide-3-kinase regulatory subunit 3, phosphoinositide-3-kinase, regulatory subunit 3 (gamma), PI3K regulatory subunit gamma, PI3-kinase p85 subunit gamma, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, Pik3r3, ptdIns-3-kinase p85-gamma, ptdIns-3-kinase regulatory subunit gamma, ptdIns-3-kinase regulatory subunit p55-gamma, RP4-533D7.2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18710, 60664, 8503

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity
  • During insulin stimulation, it also binds to IRS-1
  • It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits
  • The protein is expressed at highest levels in brain and testis
  • Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle
  • The protein contains 2 SH2 domains.