GCLM Recombinant Rabbit Monoclonal Antibody (JM39-61), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532783-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532783 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
GCLM
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O09172, P48507, P48508
Gene Symbols
Gclm
Immunogen
Recombinant protein within Human GCLM aa 225-274
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JM39-61
Conjugate
Unconjugated
Gene
Gclm
Gene Alias
AI649393, gamma glutamylcysteine synthetase, gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Gclm, Gcmc, GCS light chain, Glclr, glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory, glutamate cysteine ligase, modifier subunit, glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD), glutamate-cysteine ligase modifier subunit, glutamate--cysteine ligase modifier subunit, glutamate-cysteine ligase modifier subunit delta2 alternative splicing, glutamate-cysteine ligase regulatory protein, Glutamate--cysteine ligase regulatory subunit, glutamate-cysteine ligase, modifier subunit, GSC light chain, null
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14630, 2730, 29739
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis
- GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant
- Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.