Phospho-PRKAR2A (Ser99) Recombinant Rabbit Monoclonal Antibody (SC54-04), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532203-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532203 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Phospho-PRKAR2A (Ser99)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P12367, P12368, P13861
Gene Symbols
PRKAR2A
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser99 of Human PKA R2 aa 82-126
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SC54-04
Conjugate
Unconjugated
Gene
PRKAR2A
Gene Alias
1110061A24Rik, AI317181, AI836829, cAMP-dependent protein kinase regulatory subunit RII alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase, regulatory subunit alpha 2, MGC3606, PKR2, PRKAR2, Prkar2a, protein kinase A, RII-alpha subunit, protein kinase cAMP-dependent regulatory type II alpha, protein kinase cAMP-dependent type II regulatory subunit alpha, protein kinase, cAMP dependent regulatory, type II alpha, protein kinase, cAMP-dependent, regulatory subunit type II alpha, protein kinase, cAMP-dependent, regulatory, type 2, alpha, protein kinase, cAMP-dependent, regulatory, type II, alpha, RII(alpha), unnamed protein product
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
19087, 29699, 397493, 5576
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- cAMP is a signaling molecule important for a variety of cellular functions
- cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins
- The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits
- cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
- Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans
- The protein encoded by this gene is one of the regulatory subunits
- This subunit can be phosphorylated by the activated catalytic subunit
- It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.