RAB9 Recombinant Rabbit Monoclonal Antibody (SR45-05), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531997-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA531997 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
RAB9
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P51151, Q99P75, Q9R0M6
Gene Symbols
Rab9, Rab9a
Immunogen
Synthetic peptide within Human Rab9 aa 31-80
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SR45-05
Conjugate
Unconjugated
Gene
Rab9a
Gene Alias
2410064E05Rik, AI195561, rab9, rab9 GTP-binding protein, RAB9, member RAS oncogene family, Rab9a, rab-9A, RAB9A, member RAS oncogene family, RAB9-like protein, ras-related protein Rab-9A, Sid 99, Sid6061p, Sid99
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
56382, 84589, 9367
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport
- Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell
- Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN)
- By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components
- It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus
- Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol
- GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.