PIMA532683

Profilin 1 Recombinant Rabbit Monoclonal Antibody (JA30-13), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532683-Each-of-1 In Stock ₹ 47,481.50

PIMA532683 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Profilin 1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P07737, P62962, P62963

Gene Symbols

Pfn1

Immunogen

Synthetic peptide within Human Profilin 1 aa 91-140

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JA30-13

Conjugate

Unconjugated

Gene

Pfn1

Gene Alias

actin binding protein, ALS18, Epididymis tissue protein Li 184a, Pfn, Pfn1, profilin 1, profilin I, Profilin-1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18643, 5216, 64303

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics
  • There are two mammalian profilins with similar biochemical properties but different expression patterns
  • Profilin I appears to be highly expressed in most tissues except for skeletal muscle
  • Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney
  • Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.