Phospho-Rb (Ser807) Recombinant Rabbit Monoclonal Antibody (SR3-82), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532005-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532005 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Phospho-Rb (Ser807)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P06400, P13405, P33568
Gene Symbols
RB1
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser807 of human Rb
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SR3-82
Conjugate
Unconjugated
Gene
RB1
Gene Alias
Cleaved Rb, delta RB-p70, DRb-p70, exon 17 tumor GOS561 substitution mutation causes premature stop, GOS563 exon 17 substitution mutation causes premature stop, OSRC, p104, p104 chicken Rb, P105RB, p105-Rb, Phospho-Retinoblastoma, pp105, pp110, PPP1R130, pRb, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, rb, RB transcriptional corepressor 1, RB1, Rb-1, Rb-p70, Retin, Retinoblastoma, retinoblastoma 1, retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 protein, retinoblastoma gene, retinoblastoma isoform A, retinoblastoma protein, retinoblastoma suspectibility protein, retinoblastoma tumor suppressor, retinoblastoma-associated protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
19645, 24708, 5925
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA
- It is phosphorylated on serine and threonine, but not on tyrosine residues
- It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E
- Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth
- Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.