PIMA532008

beta-5 Tubulin Recombinant Rabbit Monoclonal Antibody (SR25-04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532008-Each-of-1 In Stock ₹ 46,413.50

PIMA532008 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

beta-5 Tubulin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P07437, P69897, P99024

Gene Symbols

TUBB, Tubb5

Immunogen

Synthetic peptide within Human beta Tubulin aa 308-357

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SR25-04

Conjugate

Unconjugated

Gene

TUBB

Gene Alias

AA408537, AI596182, B130022C14Rik, beta Ib tubulin, CDCBM6, CSCSC1, M(beta)5, M40, OK/SW-cl.56, tbb5, TUBB, TUBB1, TUBB5, tubulin beta, Tubulin beta chain, tubulin beta class I, tubulin beta-1 chain, tubulin beta-5 chain, tubulin, beta 5 class I, tubulin, beta class I, tubulin, beta polypeptide

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

203068, 22154, 29214

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tublin, which is a dimer of two 55kDa subunits: alpha and Beta
  • Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton
  • This antibody does not cause the 10-nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps
  • It does not block microtubule assembly
  • Ab-3 does not inhibit polymerization or depolymerization of platelet tubulin in vitro
  • It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.