ATF2 Recombinant Rabbit Monoclonal Antibody (SZ17-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532022-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532022 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
ATF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P15336, P16951
Gene Symbols
Atf2
Immunogen
Synthetic peptide within Human ATF2 aa 456-505
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SZ17-01
Conjugate
Unconjugated
Gene
Atf2
Gene Alias
Activating 2, Activating transcription factor 2, activating transcription factor 2 splice variant ATF2-var2, ATF2, Atf-2, cAMP response element-binding protein CRE-BP1, cAMP responsive element binding protein 2, formerly, cAMP-dependent transcription factor ATF-2, CREB2, CREB-2, CRE-BP, CREBP1, CRE-BP1, Cyclic AMP-dependent transcription factor ATF-2, cyclic AMP-responsive element-binding protein 2, D130078H02Rik, D18875, HB16, Histone acetyltransferase ATF2, MGC111558, mXBP, MXBP protein, OTTHUMP00000205345, OTTHUMP00000205347, OTTHUMP00000205348, OTTHUMP00000205350, OTTHUMP00000205352, OTTHUMP00000205353, OTTHUMP00000205354, Tg(Gzma-Klra1)7Wum, TREB7
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11909, 1386
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins
- ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways
- Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2
- Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71
- Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.